Junb^tm2Wag
Targeted Allele Detail

Summary

• Symbol: Junb^tm2Wag
• Name: jun B proto-oncogene; targeted mutation 2, Erwin F Wagner
• MGI ID: MGI:2153822
• Synonyms: junB-
• Gene: Junb Location: Chr8:85703538-85705377 bp, - strand Genetic Position: Chr8, 41.41 cM, cytoband C2-D1
• Alliance: Junb^tm2Wag page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:53304
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 486bp fragment encoding the DNA binding and protein dimerization domains was replaced with a promoterless hygromycin resistance gene. The resulting mutation fused the first 236 codons to the second codon of the hygromycin gene. (J:53304)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Junb Mutation: 19 strains or lines available

References

• Original: J:53304 Schorpp-Kistner M, et al., JunB is essential for mammalian placentation. EMBO J. 1999 Feb 15;18(4):934-48
• All: 1 reference(s)