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Fgfr2tm1.1Dsn
Targeted Allele Detail
Nomenclature
Symbol: Fgfr2tm1.1Dsn
Name: fibroblast growth factor receptor 2; targeted mutation 1.1, Clive Dickson
MGI ID: MGI:2153811
Synonyms: Fgfr2b-, Fgfr2(IIIb)-, FgfR2-IIIb-Cre
Gene: Fgfr2  Location: Chr7:130162451-133123350 bp, - strand  Genetic Position: Chr7, 73.19 cM
Palatal abnormalities in Fgfr2tm1.1Dsn/Fgfr2tm1.1Dsn and Fgf10tm1Wss/Fgf10tm1Wss mice

Show the 5 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:59285
Parent Cell Line:  GK129 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 41 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fgfr2 Mutation:  18 strains or lines available
References
Original:  J:59285 De Moerlooze L, et al., An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal-epithelial signalling during mouse organogenesis. Development. 2000 Feb;127(3):483-92
All:  20 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory