About   Help   FAQ
Bgntm1Mfy
Targeted Allele Detail
Nomenclature
Symbol: Bgntm1Mfy
Name: biglycan; targeted mutation 1, Marian F Young
MGI ID: MGI:2153057
Synonyms: Bgn-/0, bgn-KO
Gene: Bgn  Location: ChrX:73483602-73495933 bp, + strand  Genetic Position: ChrX, 37.33 cM, cytoband B
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:49647
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation details
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Bgn Mutation:  3 strains or lines available
Notes
Phenotypic Similarity to Human Syndrome: Preterm premature rupture of fetal membranes (PPROM; J:180914) in mice homozygous for Bgntm1Mfy and Dcntm1Ioz
Phenotypic Similarity to Human Syndrome: Ehlers-Danlos syndrome, progeroid type in mice homozygous or hemizygous for for Bgntm1Mfy and homozygous for Dcntm1Ioz (J:91512)

References
Original:  J:49647 Xu T, et al., Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in mice. Nat Genet. 1998 Sep;20(1):78-82
All:  37 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/23/2014
MGI 5.19
The Jackson Laboratory