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Targeted Allele Detail
Symbol: Mttptm2Sgy
Name: microsomal triglyceride transfer protein; targeted mutation 2, Steven G Young
MGI ID: MGI:2152202
Synonyms: Mttpfl
Gene: Mttp  Location: Chr3:138089855-138143418 bp, - strand  Genetic Position: Chr3, 64.06 cM
Germline Transmission:  Earliest citation of germline transmission: J:54612
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsA neomycin resistance cassette flanked by loxP sites was inserted into intron 1. An additional loxP site was inserted 2.5 kb upstream of the promoter and exon 1. (J:54612)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Mttp Mutation:  27 strains or lines available
Original:  J:54612 Raabe M, et al., Analysis of the role of microsomal triglyceride transfer protein in the liver of tissue-specific knockout mice. J Clin Invest. 1999 May;103(9):1287-98
All:  40 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
The Jackson Laboratory