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Hoxb3tm1Mrc
Targeted Allele Detail
Nomenclature
Symbol: Hoxb3tm1Mrc
Name: homeobox B3; targeted mutation 1, Mario R Capecchi
MGI ID: MGI:2151773
Synonyms: Hoxb3-
Gene: Hoxb3  Location: Chr11:96323326-96347930 bp, + strand  Genetic Position: Chr11, 59.84 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:45337
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 225 bp fragment of the gene encoding the entire homeobox domain was replaced with a neomycin cassette. (J:45337)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxb3 Mutation:  6 strains or lines available
References
Original:  J:45337 Manley NR, et al., Hox group 3 paralogous genes act synergistically in the formation of somitic and neural crest-derived structures. Dev Biol. 1997 Dec 15;192(2):274-88
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory