About   Help   FAQ
Hoxb2tm1Mrc
Targeted Allele Detail
Nomenclature
Symbol: Hoxb2tm1Mrc
Name: homeobox B2; targeted mutation 1, Mario R Capecchi
MGI ID: MGI:2151772
Synonyms: hoxb-2-
Gene: Hoxb2  Location: Chr11:96351632-96354020 bp, + strand  Genetic Position: Chr11, 59.85 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:37682
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    A neomycin cassette was inserted into the sequences encoding the homeobox domain in exon 2. (J:37682)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 6 assay results
In Structures Affected by this Mutation: 9 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxb2 Mutation:  1 strain or line available
References
Original:  J:37682 Barrow JR, et al., Targeted disruption of the Hoxb-2 locus in mice interferes with expression of Hoxb-1 and Hoxb-4. Development. 1996 Dec;122(12):3817-28
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/26/2020
MGI 6.15
The Jackson Laboratory