About   Help   FAQ
Scxtm2Eno
Targeted Allele Detail
Nomenclature
Symbol: Scxtm2Eno
Name: scleraxis; targeted mutation 2, Eric N Olson
MGI ID: MGI:2151296
Synonyms: scleraxis -
Gene: Scx  Location: Chr15:76457438-76459468 bp, + strand  Genetic Position: Chr15, 35.92 cM
Mutation
origin
Mouse Generated:  Earliest citation of chimera generation: J:55991
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S7/SvEvBrd and C57BL/6 and Swiss
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA PGK-hygromycin resistance cassette replaced exon 1 of the wild-type Scx allele in heterozygous ES cells (Gt(ROSA)26Sor+/- Scxtm1Eno-+/-). Injection of lacZ-marked Scxtm1Eno/Scxtm2Eno ES cells into wild-type blastocysts resulted in chimeric embryos. (J:55991)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Scx Mutation:  4 strains or lines available
References
Original:  J:55991 Brown D, et al., Dual role of the basic helix-loop-helix transcription factor scleraxis in mesoderm formation and chondrogenesis during mouse embryogenesis. Development. 1999 Oct;126(19):4317-29
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/05/2017
MGI 6.11
The Jackson Laboratory