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Hoxa13tm2Ipc
Targeted Allele Detail
Nomenclature
Symbol: Hoxa13tm2Ipc
Name: homeobox A13; targeted mutation 2, I Pierre Chambon
MGI ID: MGI:2150507
Gene: Hoxa13  Location: Chr6:52257694-52260803 bp, - strand  Genetic Position: Chr6, 25.41 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:36214
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin cassette replaced exon 1, intron 1, exon 2 and part of intron 2, effectively deleting the Hoxa13 gene. (J:36214)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 20 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxa13 Mutation:  21 strains or lines available
References
Original:  J:36214 Fromental-Ramain C, et al., Hoxa-13 and Hoxd-13 play a crucial role in the patterning of the limb autopod. Development. 1996 Oct;122(10):2997-3011
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory