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Slc7a2tm1Clm
Targeted Allele Detail
Nomenclature
Symbol: Slc7a2tm1Clm
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 2; targeted mutation 1, Carol L MacLeod
MGI ID: MGI:2150359
Synonyms: Cat2 -
Gene: Slc7a2  Location: Chr8:41315404-41375107 bp, + strand  Genetic Position: Chr8, 23.89 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:69414
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A neomycin resistance cassette replaced 1.9 kb of sequence, including exon 2. (J:69414)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Slc7a2 Mutation:  39 strains or lines available
References
Original:  J:69414 Nicholson B, et al., Sustained nitric oxide production in macrophages requires the arginine transporter CAT2. J Biol Chem. 2001 May 11;276(19):15881-5
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/16/2021
MGI 6.17
The Jackson Laboratory