About   Help   FAQ
Fgf8tm1.3Mrt
Targeted Allele Detail
Nomenclature
Symbol: Fgf8tm1.3Mrt
Name: fibroblast growth factor 8; targeted mutation 1.3, Gail R Martin
MGI ID: MGI:2150347
Synonyms: Fgf8clc, Fgf8fl, Fgf8flox
Gene: Fgf8  Location: Chr19:45736798-45742915 bp, - strand  Genetic Position: Chr19, 38.75 cM, cytoband C3-D
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:45909
Parent Cell Line:  HM-1 (ES Cell)
Strain of Origin:  129P2/OlaHsd-Hprtb-m3
Mutation
description
Allele Type:    Targeted (Floxed/Frt)
Mutation:    Insertion
 
Mutation details
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Mice Carrying this Mutation: 47 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fgf8 Mutation:  4 strains or lines available
Notes
One of three alleles produced using a targeting construct capable of inducing different allelic variants when mated to mice that express cre, flp, or both. Referred to in the literature as Fgf8flox, Flp mediated recombinase reverts the hypomorphic Fgf8neo allele to wild-type (J:45909).

References
Original:  J:45909 Meyers EN, et al., An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination. Nat Genet. 1998 Feb;18(2):136-41
All:  37 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/15/2014
MGI 5.17
The Jackson Laboratory