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Irs3tm1Lhd
Targeted Allele Detail
Nomenclature
Symbol: Irs3tm1Lhd
Name: insulin receptor substrate 3; targeted mutation 1, Gustav E Lienhard
MGI ID: MGI:2149647
Synonyms: IRS-3-, IRS3-
Gene: Irs3  Location: Chr5:137641294-137643976 bp, - strand  Genetic Position: Chr5, 76.59 cM, cytoband G2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:55667
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    A neomycin resistance cassette disrupted the coding region of the gene. (J:55667)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Irs3 Mutation:  14 strains or lines available
References
Original:  J:55667 Liu SC, et al., Insulin receptor substrate 3 is not essential for growth or glucose homeostasis. J Biol Chem. 1999 Jun 18;274(25):18093-9
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory