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Six5tm1Rdd
Targeted Allele Detail
Nomenclature
Symbol: Six5tm1Rdd
Name: sine oculis-related homeobox 5; targeted mutation 1, Sita Reddy
MGI ID: MGI:2148689
Gene: Six5  Location: Chr7:19094594-19098549 bp, + strand  Genetic Position: Chr7, 9.46 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:61881
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsReplacement of the entire coding region of the gene, including 398 bp upstream of the start codon and 180 bp downstream of the termination codon, with a neomycin cassette. (J:61881)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Six5 Mutation:  6 strains or lines available
References
Original:  J:61881 Sarkar PS, et al., Heterozygous loss of Six5 in mice is sufficient to cause ocular cataracts. Nat Genet. 2000 May;25(1):110-4
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/16/2017
MGI 6.09
The Jackson Laboratory