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Galk1tm1Stb
Targeted Allele Detail
Nomenclature
Symbol: Galk1tm1Stb
Name: galactokinase 1; targeted mutation 1, Dwight Stambolian
MGI ID: MGI:2148688
Synonyms: GK
Gene: Galk1  Location: Chr11:116008457-116012719 bp, - strand  Genetic Position: Chr11, 80.91 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:63743
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsReplacement of exons 3, 4 and 5 with a neomycin cassette. No galactokinase activity could be detected in liver extracts of homozyogous mice. (J:63743)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 5 assay results
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Galk1 Mutation:  0 strains or lines available
References
Original:  J:63743 Ai Y, et al., A mouse model of galactose-induced cataracts. Hum Mol Genet. 2000 Jul 22;9(12):1821-7
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory