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Targeted Allele Detail
Symbol: Maftm1Glm
Name: avian musculoaponeurotic fibrosarcoma oncogene homolog; targeted mutation 1, Laurie H Glimcher
MGI ID: MGI:2148636
Synonyms: c-maf-, Maf-
Gene: Maf  Location: Chr8:115703253-115706894 bp, - strand  Genetic Position: Chr8, 62.61 cM
Histological analysis of the lens from Maftm1Glm/Maf+ and Maftm1Glm/Maftm1Glm mice

Show the 1 phenotype image(s) involving this allele.

Germline Transmission:  Earliest citation of germline transmission: J:54079
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
Mutation detailsInsertion of a neomycin cassette into the codon corresponding to amino acid 170 of the encoded protein. No protein was detected in kidney extracts derived from homozygous mice. (J:54079)
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 18 assay results
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Maf Mutation:  11 strains or lines available
Original:  J:54079 Kim JI, et al., Requirement for the c-Maf transcription factor in crystallin gene regulation and lens development. Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):3781-5
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.13
The Jackson Laboratory