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Targeted Allele Detail
Symbol: Rapsntm1Jrs
Name: receptor-associated protein of the synapse; targeted mutation 1, Joshua R Sanes
MGI ID: MGI:2148091
Gene: Rapsn  Location: Chr2:91035620-91045729 bp, + strand  Genetic Position: Chr2, 50.44 cM
Germline Transmission:  Earliest citation of germline transmission: J:28777
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA neomycin resistance cassette replaced approximately 1kb of genomic sequence including part of exon 3 and intron 3. Western blot analysis did not detect the protein in muscle of homozygous mutant mice. (J:28777)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rapsn Mutation:  21 strains or lines available
Original:  J:28777 Gautam M, et al., Failure of postsynaptic specialization to develop at neuromuscular junctions of rapsyn-deficient mice [see comments]. Nature. 1995 Sep 21;377(6546):232-6
All:  9 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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