About   Help   FAQ
Rapsntm1Jrs
Targeted Allele Detail
Nomenclature
Symbol: Rapsntm1Jrs
Name: receptor-associated protein of the synapse; targeted mutation 1, Joshua R Sanes
MGI ID: MGI:2148091
Gene: Rapsn  Location: Chr2:91035620-91045729 bp, + strand  Genetic Position: Chr2, 50.44 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:28777
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance cassette replaced approximately 1kb of genomic sequence including part of exon 3 and intron 3. Western blot analysis did not detect the protein in muscle of homozygous mutant mice. (J:28777)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rapsn Mutation:  21 strains or lines available
References
Original:  J:28777 Gautam M, et al., Failure of postsynaptic specialization to develop at neuromuscular junctions of rapsyn-deficient mice [see comments]. Nature. 1995 Sep 21;377(6546):232-6
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/14/2017
MGI 6.11
The Jackson Laboratory