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Rettm1Cos
Targeted Allele Detail
Nomenclature
Symbol: Rettm1Cos
Name: ret proto-oncogene; targeted mutation 1, Frank Costantini
MGI ID: MGI:2136894
Synonyms: c-ret-, Ret-, ret-k-
Gene: Ret  Location: Chr6:118151748-118197744 bp, - strand  Genetic Position: Chr6, 55.86 cM, cytoband E3-F1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:23852
Parent Cell Line:  CCE/EK.CCE (ES Cell)
Strain of Origin:  129S/SvEv-Gpi1c
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Generation of the Rettm6.1Vpa and Rettm6.2Vpa alleles
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 23 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Ret Mutation:  24 strains or lines available
References
Original:  J:23852 Schuchardt A, et al., Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret [see comments]. Nature. 1994 Jan 27;367(6461):380-3
All:  41 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory