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Gdnftm1Lmgd
Targeted Allele Detail
Nomenclature
Symbol: Gdnftm1Lmgd
Name: glial cell line derived neurotrophic factor; targeted mutation 1, Laboratory of Mammalian Genes and Development, Heiner Westphal
MGI ID: MGI:2136846
Synonyms: Gdnf-
Gene: Gdnf  Location: Chr15:7811011-7837575 bp, + strand  Genetic Position: Chr15, 3.8 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:33810
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Replacement of part of the third exon with a neomycin cassette. (J:33810)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gdnf Mutation:  5 strains or lines available
Notes
ES cell line = J1 (129S4/SvJae) or R1 ((129X1/SvJ x 129S1/Sv)F1-Kitl+).

References
Original:  J:33810 Pichel JG, et al., Defects in enteric innervation and kidney development in mice lacking GDNF. Nature. 1996 Jul 4;382(6586):73-6
All:  35 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory