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Myf5tm3(cre)Sor
Targeted Allele Detail
Summary
Symbol: Myf5tm3(cre)Sor
Name: myogenic factor 5; targeted mutation 3, Philippe Soriano
MGI ID: MGI:2135565
Synonyms: Mif5-Cre, Myf5Cre, Myf5Cre-So, Myf5CreSOR, myf5-CreTG
Gene: Myf5  Location: Chr10:107318769-107321995 bp, - strand  Genetic Position: Chr10, 55.95 cM
Alliance: Myf5tm3(cre)Sor page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:65301
Parent Cell Line:  AK7 (ES Cell)
Strain of Origin:  129S4/SvJaeSor
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Myf5tm3(cre)Sor expression driven by 1 gene
 
Mutation detailsA cre cDNA was inserted between a SacI site and a KpnI site in the 5'UTR of the Myf5 gene. An adjacent loxP-flanked neomycin cassette was removed by Cre- mediated recombination. (J:65301)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Myf5 (mouse)
Summary of all recombinase alleles driven by Myf5.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 259 assay results
7 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Myf5 Mutation:  17 strains or lines available
References
Original:  J:65301 Tallquist MD, et al., Early myotome specification regulates PDGFA expression and axial skeleton development. Development. 2000 Dec;127(23):5059-70
All:  149 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory