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Abca1tm1Wpfl
Targeted Allele Detail
Nomenclature
Symbol: Abca1tm1Wpfl
Name: ATP-binding cassette, sub-family A (ABC1), member 1; targeted mutation 1, Wai-Ping Fung-Leung
MGI ID: MGI:1935193
Synonyms: ABCA1-
Gene: Abca1  Location: Chr4:53030787-53159895 bp, - strand  Genetic Position: Chr4, 28.57 cM, cytoband A5-B3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:64390
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Abca1 Mutation:  9 strains or lines available
References
Original:  J:64390 Christiansen-Weber TA, et al., Functional loss of ABCA1 in mice causes severe placental malformation, aberrant lipid distribution, and kidney glomerulonephritis as well as high-density lipoprotein cholesterol deficiency. Am J Pathol. 2000 Sep;157(3):1017-29
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory