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Soat1tm1Ishi
Targeted Allele Detail
Nomenclature
Symbol: Soat1tm1Ishi
Name: sterol O-acyltransferase 1; targeted mutation 1, Shun Ishibashi
MGI ID: MGI:1934032
Synonyms: ACAT-1
Gene: Soat1  Location: Chr1:156424525-156474331 bp, - strand  Genetic Position: Chr1, 67.71 cM
Narrow eye fissures and atrophic meibomian glands in Soat1tm1Ishi/Soat1tm1Ishi mice

Show the 3 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:63468
Parent Cell Line:  JH1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Soat1 Mutation:  10 strains or lines available
References
Original:  J:63468 Yagyu H, et al., Absence of ACAT-1 attenuates atherosclerosis but causes dry eye and cutaneous xanthomatosis in mice with congenital hyperlipidemia. J Biol Chem. 2000 Jul 14;275(28):21324-30
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory