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Ntf3tm1Par
Targeted Allele Detail
Nomenclature
Symbol: Ntf3tm1Par
Name: neurotrophin 3; targeted mutation 1, Luis F Parada
MGI ID: MGI:1933844
Synonyms: NT-3-, NT-3BRP, NT-3neo
Gene: Ntf3  Location: Chr6:126101412-126166910 bp, - strand  Genetic Position: Chr6, 60.45 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:67562
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    A neomycin cassette was inserted into the only coding exon, disrupting gene function. (J:67562, J:97779)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 6 assay results
In Structures Affected by this Mutation: 40 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ntf3 Mutation:  17 strains or lines available
References
Original:  J:67562 Tessarollo L, et al., Targeted mutation in the neurotrophin-3 gene results in loss of muscle sensory neurons. Proc Natl Acad Sci U S A. 1994 Dec 6;91(25):11844-8
All:  15 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/08/2018
MGI 6.12
The Jackson Laboratory