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Msx1tm1Bero
Targeted Allele Detail
Nomenclature
Symbol: Msx1tm1Bero
Name: msh homeobox 1; targeted mutation 1, Benoit Robert
MGI ID: MGI:1933766
Synonyms: Msx1-, Msx1nlacZ, Msx1-nlacZ
Gene: Msx1  Location: Chr5:37820491-37824585 bp, - strand  Genetic Position: Chr5, 20.21 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:42035
Parent Cell Line:  HM-1 (ES Cell)
Strain of Origin:  129P2/OlaHsd-Hprtb-m3
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsAn n-lacZ reporter gene was inserted in-frame into the sequence encoding the third helix of the homeodomain. A fusion protein of the first 43 amino acids and beta-galactosidase is expressed from this allele. (J:42035)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 168 assay results
In Structures Affected by this Mutation: 21 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Msx1 Mutation:  6 strains or lines available
References
Original:  J:42035 Houzelstein D, et al., Insertional mutation of the mouse Msx1 homeobox gene by an nlacZ reporter gene. Mech Dev. 1997 Jul;65(1-2):123-33
All:  28 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/09/2019
MGI 6.13
The Jackson Laboratory