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Cdkn1atm1Tyj
Targeted Allele Detail
Nomenclature
Symbol: Cdkn1atm1Tyj
Name: cyclin-dependent kinase inhibitor 1A (P21); targeted mutation 1, Tyler Jacks
MGI ID: MGI:1933751
Synonyms: Cdkn1a-, p21-, p21cip-
Gene: Cdkn1a  Location: Chr17:29090979-29100722 bp, + strand  Genetic Position: Chr17, 15.12 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:68068
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Inheritance:    Recessive
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 3 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Cdkn1a Mutation:  44 strains or lines available
References
Original:  J:68068 Brugarolas J, et al., Radiation-induced cell cycle arrest compromised by p21 deficiency. Nature. 1995 Oct 12;377(6549):552-7
All:  132 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory