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Cenpbtm1Rpe
Targeted Allele Detail
Nomenclature
Symbol: Cenpbtm1Rpe
Name: centromere protein B; targeted mutation 1, Roger A Pedersen
MGI ID: MGI:1932104
Synonyms: CENP-B null
Gene: Cenpb  Location: Chr2:131175182-131180067 bp, - strand  Genetic Position: Chr2, 63.29 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:50001
Parent Cell Line:  JM-1 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance cassette replaced 660 bp of coding sequence. Northern and Western blot analyses of lung fibroblasts did not detect Cenpb transcript or protein in homozygous mutant mice. (J:50001)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cenpb Mutation:  5 strains or lines available
References
Original:  J:50001 Perez-Castro AV, et al., Centromeric protein B null mice are viable with no apparent abnormalities. Dev Biol. 1998 Sep 15;201(2):135-43
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory