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Acvr1tm1Bhr
Targeted Allele Detail
Nomenclature
Symbol: Acvr1tm1Bhr
Name: activin A receptor, type 1; targeted mutation 1, Richard R Behringer
MGI ID: MGI:1931734
Synonyms: Alk2delta5
Gene: Acvr1  Location: Chr2:58388644-58567157 bp, - strand  Genetic Position: Chr2, 33.05 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:57670
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A 3.1 kb segment of the gene, including exon 5, was replaced with a PGK-hprt expression cassette. (J:57670)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 17 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Acvr1 Mutation:  22 strains or lines available
References
Original:  J:57670 Mishina Y, et al., Multiple roles for activin-like kinase-2 signaling during mouse embryogenesis. Dev Biol. 1999 Sep 15;213(2):314-26
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory