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Tg(WapNotch4)10Rnc
Transgene Detail
Nomenclature
Symbol: Tg(WapNotch4)10Rnc
Name: transgene insertion 10, Robert Callahan
MGI ID: MGI:1930202
Synonyms: Tg(WapInt3)10Rnc, WAP/Int3, Wap-int3 tg
Transgene: Tg(WapNotch4)10Rnc  Location: unknown  Genetic Position: ChrX, Syntenic
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(WapNotch4)10Rnc expresses 1 gene
 
Mutation detailsThe transgene insert consisted of the mouse whey acidic acid promoter and the portion of the Notch4 gene encoding the intracellular domain. Wap promoter activity is restricted to the secretory mammary epithelial population. Four founder mice were identified. One line established from founder 10. Transmission analysis indicates that the transgene inserted into the X chromosome. (J:33193)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:33193 Gallahan D, et al., Expression of a truncated Int3 gene in developing secretory mammary epithelium specifically retards lobular differentiation resulting in tumorigenesis. Cancer Res. 1996 Apr 15;56(8):1775-85
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory