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Gdf9tm1Zuk
Targeted Allele Detail
Summary
Symbol: Gdf9tm1Zuk
Name: growth differentiation factor 9; targeted mutation 1, Martin M Matzuk
MGI ID: MGI:1930111
Synonyms: Gdf9-, Gdf9m1
Gene: Gdf9  Location: Chr11:53321850-53328731 bp, + strand  Genetic Position: Chr11, 31.94 cM
Alliance: Gdf9tm1Zuk page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:35782
Parent Cell Line:  AB2.1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt1b-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThe deletion targeting vector generated a 1.1kb deletion including exon 2 which encodes the majority of the propeptide sequence and the complete mature sequence. (J:35782)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 11 assay results
1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gdf9 Mutation:  33 strains or lines available
References
Original:  J:35782 Dong J, et al., Growth differentiation factor-9 is required during early ovarian folliculogenesis [see comments]. Nature. 1996 Oct 10;383(6600):531-5
All:  19 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory