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Targeted Allele Detail
Symbol: Foxf1tm1Pca
Name: forkhead box F1; targeted mutation 1, Peter Carlsson
MGI ID: MGI:1929432
Synonyms: Foxf1-
Gene: Foxf1  Location: Chr8:121084386-121088144 bp, + strand  Genetic Position: Chr8, 70.31 cM, cytoband E1
Germline Transmission:  Earliest citation of germline transmission: J:66591
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Replacement of sequences encoding the forkhead box with a neomycin cassette. (J:66591)
Inheritance:    Recessive
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 46 assay results
In Structures Affected by this Mutation: 6 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Foxf1 Mutation:  1 strain or line available
The targeting construct was electroporated into two ES cell lines, RW4, derived from 129X1/SvJ, and E14, derived from 129P2/OlaHsd.
Original:  J:66591 Mahlapuu M, et al., The forkhead transcription factor Foxf1 is required for differentiation of extra-embryonic and lateral plate mesoderm. Development. 2001 Jan;128(2):155-66
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory