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Erbb2tm1Haus
Targeted Allele Detail
Nomenclature
Symbol: Erbb2tm1Haus
Name: erb-b2 receptor tyrosine kinase 2; targeted mutation 1, Christopher Hauser
MGI ID: MGI:1929070
Synonyms: erbB2-
Gene: Erbb2  Location: Chr11:98412484-98437716 bp, + strand  Genetic Position: Chr11, 61.75 cM, cytoband D
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:29973
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A PGK-neomycin cassette replaced 2.0 kb of sequence containing the promoter and first exon. (J:29973)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 15 assay results
In Structures Affected by this Mutation: 12 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Erbb2 Mutation:  5 strains or lines available
References
Original:  J:29973 Lee KF, et al., Requirement for neuregulin receptor erbB2 in neural and cardiac development [see comments]. Nature. 1995 Nov 23;378(6555):394-8
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/04/2020
MGI 6.14
The Jackson Laboratory