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Dbhtm2(Th)Rpa
Targeted Allele Detail
Nomenclature
Symbol: Dbhtm2(Th)Rpa
Name: dopamine beta hydroxylase; targeted mutation 2, Richard D Palmiter
MGI ID: MGI:1928960
Synonyms: DbhTh, DBH-TH-
Gene: Dbh  Location: Chr2:27165507-27183204 bp, + strand  Genetic Position: Chr2, 19.29 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:30404
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted
Mutation:    Insertion
 
Mutation detailsThe entire Th coding region, including 1kb sequence after the polyadenylation site and a neomycin resistance cassette, was inserted between exons 1 and 2 of the Dbh gene. (J:30404)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Dbh Mutation:  7 strains or lines available
References
Original:  J:30404 Zhou QY, et al., Dopamine-deficient mice are severely hypoactive, adipsic, and aphagic. Cell. 1995 Dec 29;83(7):1197-209
All:  23 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/12/2019
MGI 6.13
The Jackson Laboratory