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Nkx3-1tm1Siz
Targeted Allele Detail
Nomenclature
Symbol: Nkx3-1tm1Siz
Name: NK-3 transcription factor, locus 1 (Drosophila); targeted mutation 1, Seigo Izumo
MGI ID: MGI:1928655
Synonyms: Nkx3.1 -
Gene: Nkx3-1  Location: Chr14:69190638-69194662 bp, + strand  Genetic Position: Chr14, 36.02 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:64981
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 2, encoding the homeodomain and NK-2 specific domain were deleted and replaced by a neomycin cassette. (J:64981)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nkx3-1 Mutation:  10 strains or lines available
References
Original:  J:64981 Tanaka M, et al., Nkx3.1, a murine homolog of drosophila bagpipe, regulates epithelial ductal branching and proliferation of the prostate and palatine glands. Dev Dyn. 2000 Oct;219(2):248-60
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory