About   Help   FAQ
Grin1tm1Cur
Targeted Allele Detail
Nomenclature
Symbol: Grin1tm1Cur
Name: glutamate receptor, ionotropic, NMDA1 (zeta 1); targeted mutation 1, Tom Curran
MGI ID: MGI:1928327
Synonyms: GluR1-, NR1-
Gene: Grin1  Location: Chr2:25291181-25319187 bp, - strand  Genetic Position: Chr2, 17.14 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:66345
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A neomycin cassette replaced 1.6 kb of sequence including the first coding exon. (J:66345)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Grin1 Mutation:  17 strains or lines available
References
Original:  J:66345 Forrest D, et al., Targeted disruption of NMDA receptor 1 gene abolishes NMDA response and results in neonatal death. Neuron. 1994 Aug;13(2):325-38
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/11/2020
MGI 6.14
The Jackson Laboratory