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Targeted Allele Detail
Symbol: Grin1tm2Stl
Name: glutamate receptor, ionotropic, NMDA1 (zeta 1); targeted mutation 2, Susumu Tonegawa
MGI ID: MGI:1928279
Synonyms: Flox-B, floxed-NR1, fNR1, NR1flox
Gene: Grin1  Location: Chr2:25291181-25319187 bp, - strand  Genetic Position: Chr2, 17.14 cM
Germline Transmission:  Earliest citation of germline transmission: J:37457
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsInsertion of loxP sites flanking the entire transmembrane region (exons 11-21 through the 3' end of the gene). (J:37457)
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Grin1 Mutation:  12 strains or lines available
Original:  J:37457 Tsien JZ, et al., The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory [see comments]. Cell. 1996 Dec 27;87(7):1327-38
All:  57 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 5.21
The Jackson Laboratory