About   Help   FAQ
Cd74tm1Doi
Targeted Allele Detail
Nomenclature
Symbol: Cd74tm1Doi
Name: CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated); targeted mutation 1, Christophe Benoist and Diane Mathis
MGI ID: MGI:1927205
Synonyms: Cd74tm1Dim, Ii-, Ii0
Gene: Cd74  Location: Chr18:60803848-60812646 bp, + strand  Genetic Position: Chr18, 34.41 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:4119
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Replacement of exons 2 and 3 with a neomycin resistance gene. (J:4119)
Inheritance:    Recessive
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cd74 Mutation:  23 strains or lines available
References
Original:  J:4119 Viville S, et al., Mice lacking the MHC class II-associated invariant chain. Cell. 1993 Feb 26;72(4):635-48
All:  30 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/04/2018
MGI 6.13
The Jackson Laboratory