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Crebbptm1Dli
Targeted Allele Detail
Nomenclature
Symbol: Crebbptm1Dli
Name: CREB binding protein; targeted mutation 1, David Livingston
MGI ID: MGI:1926888
Synonyms: CBP-
Gene: Crebbp  Location: Chr16:4081328-4213997 bp, - strand  Genetic Position: Chr16, 2.4 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:60630
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Replacement of two exons encoding the CH1 domain of the Crebbp gene with a neomycin cassette. (J:60630)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Crebbp Mutation:  62 strains or lines available
References
Original:  J:60630 Kung AL, et al., Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP. Genes Dev. 2000 Feb 1;14(3):272-7
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/12/2018
MGI 6.12
The Jackson Laboratory