About   Help   FAQ
Pdgfratm2Sor
Targeted Allele Detail
Nomenclature
Symbol: Pdgfratm2Sor
Name: platelet derived growth factor receptor, alpha polypeptide; targeted mutation 2, Philippe Soriano
MGI ID: MGI:1926728
Synonyms: alphaR2-4, alphaR4
Gene: Pdgfra  Location: Chr5:75152292-75198215 bp, + strand  Genetic Position: Chr5, 39.55 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:41814
Parent Cell Line:  AK7 (ES Cell)
Strain of Origin:  129S4/SvJaeSor
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsReplacement of intronic sequences encoding the signal peptide, and the first and second immunoglobulin domains with a loxP-flanked neomycin cassette. (J:41814)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Structures Affected by this Mutation: 26 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pdgfra Mutation:  50 strains or lines available
References
Original:  J:41814 Soriano P, The PDGF alpha receptor is required for neural crest cell development and for normal patterning of the somites. Development. 1997 JUL;124(14):2691-2700
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/15/2018
MGI 6.12
The Jackson Laboratory