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Tg(KRT16/KRT14)A2Cou
Transgene Detail
Nomenclature
Symbol: Tg(KRT16/KRT14)A2Cou
Name: transgene insertion A2, Pierre Coulombe
MGI ID: MGI:1926506
Synonyms: K16-C14
Transgene: Tg(KRT16/KRT14)A2Cou  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x C3H)F2
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(KRT16/KRT14)A2Cou expresses 2 genes
 
Mutation detailsOverexpression of a human keratin 16 (KRT16) and human keratin 14 (KRT14) chimeric gene in the basal layer of the epidermis, driven by the human keratin 14 (KRT14) promoter. (J:49421)
Inheritance:    Not Specified
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Notes
Founder number A2 is representative of a number of founders that were examined and found to be phenotypically normal. The other founder numbers were designated B1 and C1.
References
Original:  J:49421 Paladini RD, et al., Directed expression of keratin 16 to the progenitor basal cells of transgenic mouse skin delays skin maturation. J Cell Biol. 1998 Aug 24;142(4):1035-51
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory