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Msx1tm1Rilm
Targeted Allele Detail
Summary
Symbol: Msx1tm1Rilm
Name: msh homeobox 1; targeted mutation 1, Richard Maas
MGI ID: MGI:1926386
Synonyms: Msx1-
Gene: Msx1  Location: Chr5:37977835-37981929 bp, - strand  Genetic Position: Chr5, 20.21 cM
Alliance: Msx1tm1Rilm page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:17489
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsGene disruption caused by insertion of a pMC1-neo cassette into coding sequences located in the homeobox domain. (J:17489)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 330 assay results
2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 19 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Msx1 Mutation:  18 strains or lines available
References
Original:  J:17489 Satokata I, et al., Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development [see comments]. Nat Genet. 1994 Apr;6(4):348-56
All:  41 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory