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Tcf7tm1Cle
Targeted Allele Detail
Nomenclature
Symbol: Tcf7tm1Cle
Name: transcription factor 7, T cell specific; targeted mutation 1, Hans Clevers
MGI ID: MGI:1926298
Synonyms: Tcf-1-, Tcf1-, Tcf1Hom, Tcf7-, TcfdeltaVII
Gene: Tcf7  Location: Chr11:52252371-52283014 bp, - strand  Genetic Position: Chr11, 31.86 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:23255
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A 67-bp fragment encoding exon VII was replaced with a neomycin cassette. (J:23255)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tcf7 Mutation:  10 strains or lines available
References
Original:  J:23255 Verbeek S, et al., An HMG-box-containing T-cell factor required for thymocyte differentiation. Nature. 1995 Mar 2;374(6517):70-4
All:  41 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/12/2017
MGI 6.10
The Jackson Laboratory