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Ndst1tm1Hgx
Targeted Allele Detail
Nomenclature
Symbol: Ndst1tm1Hgx
Name: N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1; targeted mutation 1, Gengxi Hu
MGI ID: MGI:1889939
Synonyms: NDST-1(-)
Gene: Ndst1  Location: Chr18:60685978-60713389 bp, - strand  Genetic Position: Chr18, 34.38 cM, cytoband D2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:60280
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    A PGK-neo cassette was inserted into exon 1 to generate the null mice. (J:60280)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ndst1 Mutation:  30 strains or lines available
References
Original:  J:60280 Fan G, et al., Targeted disruption of NDST-1 gene leads to pulmonary hypoplasia and neonatal respiratory distress in mice. FEBS Lett. 2000 Feb 4;467(1):7-11
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/12/2018
MGI 6.12
The Jackson Laboratory