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C4btm1Crr
Targeted Allele Detail
Nomenclature
Symbol: C4btm1Crr
Name: complement component 4B (Chido blood group); targeted mutation 1, Michael C Carroll
MGI ID: MGI:1889070
Synonyms: C4-
Gene: C4b  Location: Chr17:34728380-34743882 bp, - strand  Genetic Position: Chr17, 18.29 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:30152
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 2 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any C4b Mutation:  2 strains or lines available
References
Original:  J:30152 Wessels MR, et al., Studies of group B streptococcal infection in mice deficient in complement component C3 or C4 demonstrate an essential role for complement in both innate and acquired immunity. Proc Natl Acad Sci U S A. 1995 Dec 5;92(25):11490-4
All:  70 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory