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E2f4tm1Lees
Targeted Allele Detail
Nomenclature
Symbol: E2f4tm1Lees
Name: E2F transcription factor 4; targeted mutation 1, Jacqueline A Lees
MGI ID: MGI:1888952
Synonyms: E2f4-
Gene: E2f4  Location: Chr8:105297663-105305369 bp, + strand  Genetic Position: Chr8, 53.04 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:64193
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (knock-out)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Inheritance:    Semidominant
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 1 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any E2f4 Mutation:  14 strains or lines available
References
Original:  J:64193 Humbert PO, et al., E2F4 is essential for normal erythrocyte maturation and neonatal viability. Mol Cell. 2000 Aug;6(2):281-91
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/15/2014
MGI 5.17
The Jackson Laboratory