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Cdkn1btm1Ako
Targeted Allele Detail
Nomenclature
Symbol: Cdkn1btm1Ako
Name: cyclin-dependent kinase inhibitor 1B; targeted mutation 1, Andrew Koff
MGI ID: MGI:1888808
Synonyms: Cdkn1btm1Kiyo, P27-, p27D51, p27delta, p27Kip1, p27Kip1 -, p27/Kip1-
Gene: Cdkn1b  Location: Chr6:134920401-134925513 bp, + strand  Genetic Position: Chr6, 65.77 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:33401
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsInsertion of a neomycin cassette into the first coding exon of the Cdkn1b gene. Allele produces an N-terminal partial protein product which authors refer to as delta51. (J:33401)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cdkn1b Mutation:  11 strains or lines available
References
Original:  J:33401 Kiyokawa H, et al., Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1). Cell. 1996 May 31;85(5):721-32
All:  65 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/07/2015
MGI 5.21
The Jackson Laboratory