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Lim2To3
Chemically induced Allele Detail
Nomenclature
Symbol: Lim2To3
Name: lens intrinsic membrane protein 2; total opacity 3
MGI ID: MGI:1862040
Synonyms: ENU-288
Gene: Lim2  Location: Chr7:43430088-43435996 bp, + strand  Genetic Position: Chr7, 28.25 cM
Mutation
origin
Strain of Origin:  (102/El x C3H/HeEl)F1
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsA G-to-T transversion in exon 2, the first coding exon, results in the non-conservative substitution of valine for glycine at amino acid position 15 of the protein. (J:46338)
Inheritance:    Dominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Lim2 Mutation:  12 strains or lines available
References
Original:  J:34877 Kerscher S, et al., Two new cataract loci, Ccw and To3, and further mapping of the Npp and Opj cataracts in the mouse. Genomics. 1996 Aug 15;36(1):17-21
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/12/2018
MGI 6.12
The Jackson Laboratory