About   Help   FAQ
Targeted Allele Detail
Symbol: Il2rgtm1Cgn
Name: interleukin 2 receptor, gamma chain; targeted mutation 1, University of Cologne
MGI ID: MGI:1861947
Synonyms: cgamma-, gamma-, gammac-, gc-, Il2rg-, IL-2Rgamma-
Gene: Il2rg  Location: ChrX:101264378-101268255 bp, - strand  Genetic Position: ChrX, 43.9 cM
Germline Transmission:  Earliest citation of germline transmission: J:22521
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsInsertion of a neomycin resistance cassette flanked by lox P sites, followed by homologous recombination and cre-mediated deletion, resulted in the excision of exons 2 - 6 of the gene. These exons encode the extracellular and transmembrane domains of the protein. (J:22521)
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Il2rg Mutation:  72 strains or lines available
Original:  J:22521 DiSanto JP, et al., Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain. Proc Natl Acad Sci U S A. 1995 Jan 17;92(2):377-81
All:  105 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.11
The Jackson Laboratory