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Fastm1Osa
Targeted Allele Detail
Nomenclature
Symbol: Fastm1Osa
Name: Fas (TNF receptor superfamily member 6); targeted mutation 1, Osaka University Medical School
MGI ID: MGI:1861923
Synonyms: Fas-, Tnfrsf6tm1Osa
Gene: Fas  Location: Chr19:34290659-34327770 bp, + strand  Genetic Position: Chr19, 29.48 cM
Histopathology of Fas-deficient mice.

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:64296
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 7 strains available      Cell Lines: 0 lines available
Carrying any Fas Mutation:  37 strains or lines available
References
Original:  J:64296 Adachi M, et al., Targeted mutation in the Fas gene causes hyperplasia in peripheral lymphoid organs and liver. Nat Genet. 1995 Nov;11(3):294-300
All:  23 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory