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Targeted Allele Detail
Symbol: Cnga2tm1Ngai
Name: cyclic nucleotide gated channel alpha 2; targeted mutation 1, J Ngai
MGI ID: MGI:1861912
Synonyms: CNG channel alpha -
Gene: Cnga2  Location: ChrX:71991849-72010218 bp, + strand  Genetic Position: ChrX, 37.15 cM, cytoband A6
Germline Transmission:  Earliest citation of germline transmission: J:36286
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA neomycin selection cassette replaced a genomic fragment containing the sequences encoding the fifth membrane-spanning region, the pore-forming region, the sixth membrane-spanning region and a portion of the carboxy-terminal tail. (J:36286, J:96894)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cnga2 Mutation:  12 strains or lines available
Original:  J:36286 Brunet LJ, et al., General anosmia caused by a targeted disruption of the mouse olfactory cyclic nucleotide-gated cation channel. Neuron. 1996 Oct;17(4):681-93
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory