About   Help   FAQ
Trp73tm1Fmc
Targeted Allele Detail
Nomenclature
Symbol: Trp73tm1Fmc
Name: transformation related protein 73; targeted mutation 1, Frank McKeon
MGI ID: MGI:1859911
Synonyms: p73 -
Gene: Trp73  Location: Chr4:154056253-154140208 bp, - strand  Genetic Position: Chr4, 83.79 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:60896
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 5 and a portion of exon 6, encoding part of the DNA binding domain, and the neighboring intronic sequences were replaced by a neomycin gene. (J:60896)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Mice Carrying this Mutation: 29 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Trp73 Mutation:  4 strains or lines available
References
Original:  J:60896 Yang A, et al., p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours. Nature. 2000 Mar 2;404(6773):99-103
All:  29 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/23/2015
MGI 5.22
The Jackson Laboratory