About   Help   FAQ
Fgf10tm1Ska
Targeted Allele Detail
Nomenclature
Symbol: Fgf10tm1Ska
Name: fibroblast growth factor 10; targeted mutation 1, Shigeaki Kato
MGI ID: MGI:1859647
Synonyms: fgf10-
Gene: Fgf10  Location: Chr13:118669791-118792115 bp, + strand  Genetic Position: Chr13, 67.14 cM, cytoband A3-A4
Submandibular gland abnormalities in Fgf10tm1Ska/Fgf10tm1Ska and Fgfr2tm1.1Dsn/Fgfr2tm1.1Dsn mice at E12.5

Show the 3 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:51966
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance cassette replaced 1.1 kb of sequence that contains the exon encoding the ATG translation initiation site and the amino terminal 110 amino acids of the encoded protein. (J:51966)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Mice Carrying this Mutation: 34 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fgf10 Mutation:  11 strains or lines available
References
Original:  J:51966 Sekine K, et al., Fgf10 is essential for limb and lung formation. Nat Genet. 1999 Jan;21(1):138-41
All:  49 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/07/2015
MGI 5.21
The Jackson Laboratory