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Myo5aflr
Spontaneous Allele Detail
Nomenclature
Symbol: Myo5aflr
Name: myosin VA; flailer
MGI ID: MGI:1858520
Synonyms: flail, flr, tb2J
Gene: Myo5a  Location: Chr9:74978297-75130970 bp, + strand  Genetic Position: Chr9, 42.26 cM
Mutation
origin
Strain of Origin:  C57BL/10J
Mutation
description
Allele Type:    Spontaneous
Mutation:    Other
 
Mutation detailsHybrid. This mutation is caused by gene shuffling between Gnb5 and Myo5a. The shuffling combines the promoter of the first two exons of Gnb5 with the C-terminal exons of Myo5a. Flailer homozygotes express transcripts of three genes: wild-type Gnb5, wild-type Myo5a and the flailer hybrid gene. (J:61324)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Myo5a Mutation:  192 strains or lines available
References
Original:  J:79827 The Jackson Laboratory Office of Genetic Resources, Registry of Remutation at The Jackson Laboratory. MGI Direct Data Submission. 1973;
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory